Edina Harsay
Assistant Professor
7041 Haworth Hall
(785) 864-5854
E-mail:

Figure 1.  Avl9 is a novel protein that functions in the late exocytic pathway in yeast (Harsay and Schekman, 2007).  This image shows myc-epitope-tagged human Avl9 localization in HeLa cells.  Expression of hAvl9-myc was regulated, and the tagged protein was detected 2.5 h after inducing expression.  The red label is TGN38, which resides primarily in the TGN, while the green label is hAvl9-myc, present only in transfected cells.  Human Avl9-myc may partially localize to the TGN and/or organelles close to it, such as recycling endosomes.  In addition, hAvl9-myc is present in punctate structures, possibly exocytic vesicles.